PUBLICATIONS

原著論文
(査読付き原著論文)*Corresponding author

147.

Evaluation of fluorous affinity using fluoroalkyl-modified silica gel and selective separation of poly-fluoroalkyl substances in organic solvents, A. Tadano, Y. Watabe, T. Tanigawa, S. K-Yamada, T. Kubo*, J. Sep. Sci., 47, 2400121, 2004

146.

Antimold Activities Using Quaternized Epoxy-Based Polymer Monoliths, T. Kubo*, M. Nakamichi, S. K-Yamada, K. Hosoya, Chromatography, 45, 55-61, 2024

145.

An initial study of cell separation based on mechanical properties using a sponge-like monolithic polymer, K. Tsuji, T. Tanigawa, Y. Tsutsumi, T. Kubo, N. Kaji*, Talanta Open, 2, 100321, 2024

144.

Enhanced molecular recognition with longer chain crosslinkers in molecularly imprinted polymers for an efficient separation of TR active substances, T. Kubo*, M. Yagishita, T. Tanigawa, S. K-Yamada, D. Nakajima, RSC Advances, 14, 12021-12029, 2024

143.

抗体薬物複合体の選択的分離に向けた固定相開発の基礎検討,  光田圭佑,久保拓也分析化学,72, 9, 357-361

142.

Rapid and Highly-Efficient Purification of Extracellular Vesicles Enabled by TiO2 hybridized Spongy-like Polymer, E. Kanao, K. Ishida, R. iIzuta, Y. Li, K. Imami, T. Tanigawa, Y. Sasaki, K. Akiyoshi, J. Adachi, K. Otsuka, Y. Ishihama, T. Kubo*, Anal. Chem. 95, 14502-14510, 2023

141.

Efficient selective adsorption of SARS-CoV-2 via the recognition of spike proteins using an affinity spongy monolith, T. Kubo*, E. Kanao, Koki Ishida, S. Minami, T. Tanigawa, R. Mizuta, Y. Sasaki, K. Otsuka, T. Kobayashi, Anal. Chem., 95, 13185-13190, 2023

140.

Development of a particle packed bed model for homogeneity evaluation of liquid chromatography column, T. Kubo*, M. Ichjikawa, T. Adachi, Y. Watabe, T. Naito, K. Otsuka, J. Chromatogr. A, 1705, 464171, 2023

139.

TRIAC disrupts cerebral thyroid hormone action via negative feedback and heterogenous distribution among organs, I. Yamauchi*, T. Hakata, Y. Ueda, T. Sugawa, R. Omagari, Y. Teramoto, SF, Nakayama, D. Nakajima, T. Kubo, N. Inagaki, iScience, 26,107135, 2023

138.

Rational Supramolecular Strategy via Halogen Bonding for Effective Halogen Recognition in Molecular Imprinting, E. Kanao, H. Osaki, T. Tanigawa, H. Takaya, T. Sano, J. Adachi, K. Otsuka, Y. Ishihama, T. Kubo*, Anal. Chem., 95, 9304-9313, 2023

137.

Rational Strategy for Space-Confined Atomic Layer Deposition, R. Kamei, T. Hosomi, M. Kanai, E. Kanao, J. Liu, T. Takahashi, W. Li, W. Tanaka, K. Nagashima, K. Nakano, K. Otsuka, T. Kubo, T. Yanagida*, ACS Appl. Mater. Interfaces, , 15, 23931-23937, 2023

136.

Protein Determination by Distance and Color Changing via PEG-based Hydrogels, Y. Manmana, T. Kubo*, K. Otsuka, Chromatography, 44, 27-32, 2023,

135.

インタクトなタンパク質のLC/MS分析へ向けたモノリス型シリカミクロトラップカラムの開発と評価,   小林宏資,和田啓男,久保拓也,大塚浩二,分析化学, 71, 341-349, 2022

134.

Classification of Extracellular Vesicles based on Surface Glycan Structures by Spongy-like Separation Media, E. Kanao, S. Wada, H. Nishida, T. Kubo*, T. Tanigawa, K. Imami, A. Shimoda, K. Umezaki, Y. Sasaki, K. Akiyoshi, J. Adachi, K. Otsuka, Y. Ishihama, Anal. Chem., 94, 18025-18033, 2022

133.

Selective Separation of Thyroid-Hormone-Receptor Binding Substances Using Molecularly Imprinted Polymers, T. Kubo*, S. Yamamoto, Y. Watabe, T. Tanigawa, D. Nakajima, K. Otsuka, ACS Appl. Bio Mater., 5, 5210-5217, 2022

132.

Identification by LC-MS/MS and LC-QTof-MS of the contributor to the thyroid hormone receptor agonist activity in effluents from sewage treatment plants, R. Omagari*, M. Yagishita, F. Shiraishi, S.F. Nakayama, M. Terasaki, T. Tanigawa, I. Yamauchi, T. Kubo, D. Nakajima, Environ. Sci. Tech., 56, 13709-13718, 2022

131.

Evaluation of human thyroid hormone receptor-antagonist activity in 691 chemical compounds using a yeast two-hybrid assay with Saccharomyces cerevisiae Y190, R. Omagari*, M. Yagishita, F. Shiraishi, R. Kamata, M. Terasaki, T. Kubo, D. Nakajima, Data in Brief, 42, 108303, 2022

130.

Evaluation of hTR-agonist activity in 802 chemical compounds using a yeast two-hybrid assay with Saccharomyces cervisiae Y190, R. Omagari*, M. Yagishita, M. Yamasaki, R. Kamata, M. Terasaki, F. Shiraishi, T. Kubo, D. Nakajima, EMCR, 2, 54-59, 2022

129.

Development of transient trapping micellar electrokinetic chromatography coupled with mass spectrometry for steroids analysis, Y. Manmana, C. Liu, H. Koino, K. Sueyoshi, F. Kitagawa, T. Kubo*, K. Otsuka, Chirality, 34(10), 1328-1337, 2022

128.

Specificity recognition for a target protein, cytochrome c using molecularly imprinted hydrogels, C. Liu, T. Kubo*, K. Otsuka, J. Mater. Chem. B, 10, 6800, 2022

127.

Development of a microfluidic dispensing device for multivariate data acquisition and application in molecularly imprinting hydrogel preparation, Y. Manmana, N. Hiraoka, T. Naito, T. Kubo*, K. Otsuka, J. Mater. Chem. B, 10, 6664, 2022

126.

Separation of glycoproteins based on sugar chains using novel stationary phases modified with PEG-conjugated boronic-acid derivatives, H. Kobayashi, Y. Masuda, H. Takaya, T. Kubo*, K. Otsuka, Anal. Chem., 94, 6882-6892, 2022

125.

Moderate Molecular Recognitions on ZnO m-Plane and Their Selective Capture/Release of Bio-related Phosphoric Acids, E. Kanao, K. Nakano, R. Kamei, T. Hosomi, Y. Ishihama, J. Adachi, T. Kubo*, K. Otsuka, T. Yanagida, Nanoscale Adv., 4, 1649-1658, 2022

124.

Selective Recovery of Estrogenic Endocrine Disruptors from 48 Environmental Samples Using a Substrate for Activity-Specific Concentration, M. Yagishita*, F. Shiraishi, T. Tanigawa, T. Kubo, S.F. Nakayama, D. Nakajima, Bull. Environ. Contam. Toxicol., 108, 658–662, 2022

123.

Study on magnetic thermal seeds coated with thermal-responsive molecularly imprinted polymers, T. Kubo*, M. Shimonaka, Y. Watabe, K. Akiyoshi, J. Balachandran, K. Otsuka, Nanocomposites, 7, 215-225, 2021

122.

Fluorescent Detection of the Target Protein via a Molecularly Imprinted Hydrogel, T. Kubo*, N. Watanabe, S. Ikari, C. Liu, E. Kanao, T. Naito, T. Sano, K. Otsuka, Anal. Methods, 13, 3086-3091, 2021

121.

Development of a database strategy based on LC/quadrupole time-of-flight MS for the screening of 75 estrogenic chemicals from treated sewage effluent, M. Yagishita*, T. Kubo, K. Otsuka, S.F. Nakayama, D. Nakajima, Sep. Sci. Plus, 4, 286-295, 2021

120.

Rational Strategy for Space-Confined Seeded Growth of ZnO Nanowires in Meter-Long Microtubes, R. Kamei, T. Hosomi, E. Kanao, M. Kanai, K. Nagashima, T. Takahashi, G. Zhang, T. Yasui, J. Terao, K. Otsuka, Y. Baba, T. Kubo, T. Yanagida*, ACS Appl. Mater. Interfaces, 13, 16812-16819, 2021

119.

Simple Chemical Detection Based on a Surface Modified Electroosmotic Pump by Interval Immobilization, T. Naito*, H. Inoue, T. Kubo, K. Otsuka, Anal. Methods, 13, 1559-1564, 2021

118.

Substituted meso-Vinyl-BODIPY as Thiol-Selective Fluorogenic Probes for Sensing Unfolded Proteins in the Endoplasmic Reticulum, H. Mu, K. Miki, T. Kubo, K. Otsuka, K. Ohe*, Chem. Commun., 57, 1818-1821, 2021

117.

エクソソームのサブクラス分離へ向けたレクチン固定化スポンジ基材の開発,   久保拓也*,加藤誠也,下田麻子,石川良賀,澤田晋一,佐々木善浩,秋吉一成,大塚浩二,分析化学,69(12), 731-735, 2020

116.

Poly(ethylene glycol) hydrogels with a boronic acid-monomer via molecular imprinting for selective removal of quinic acid gamma-lactone in coffee, E. Kanao, Y. Tsuchiya, K. Tanaka, Y. Masuda, T. Tanigawa, T. Naito, T. Sano, T. Kubo*, K. Otsuka, ACS Appl. Polym. Mater., 3, 226-232, 2020

115.

Separation of saccharides using fullerene-bonded silica monolithic columns via π interactions in liquid chromatography, H. Kobayashi, K. Okada, S. Tokuda, E. Kanao, Y. Masuda, T. Naito, H. Takaya, M. Yan, T. Kubo*, K. Otsuka, Sci. Rep., 10, 13850, 2020

114.

Controllable molecular sieving by copoly(poly(ethylene glycol) acrylate/poly(ethylene glycol) diacrylate) based hydrogels via capillary electrophoresis for DNA fragments, C. Liu, T. Kubo*, T. Naito, K. Otsuka, ACS Appl. Polym. Mater., 2, 3714-4159, 2020

113.

Online fluorescence imaging method by reducing the inequivalent photobleaching for quantitative capillary electrophoresis, C. Liu, Y. Yamaguchi, Y. Wang, X.Dou, T. Kubo*, K. Otsuka, Sens. Actuator B-Chem., 319, 128035, 2020

112.

Recognition of Polymer Terminus by Metal-Organic Frameworks Enabling Chromatographic Separation of Polymers, N. Mizutani, N. Hosono, B. Le Ouay, T. Kitao, R. Matsuura, T. Kubo, T. Uemura*, J. Am. Chem. Soc., 142, 3701-3705, 2020

111.

Tunable liquid chromatographic separation of H/D isotopologues enabled by aromatic p interactions, E. Kanao, T. Kubo*, T. Naito, T. Sano, M. Yan, N. Tanaka, K. Otsuka, Anal. Chem., 92, 4065-4072, 2020

110.

Separation of Halogenated Benzenes Enabled by Investigation of Halogen-p Interactions with Carbon Materials, E. Kanao, T. Morinaga, T. Kubo*, T. Naito, T. Matsumoto, T. Sano, M. Yan, K. Otsuka, Chem. Sci., 11, 409-418, 2020

109.

LC/QTofMS を用いた女性ホルモン様物質の網羅的分析法とその応用 柳下真由子,久保拓也,中山祥嗣,中島大介*,地球環境,Vol. 24-No. 1, 15-22, 2019

108.

Recycle Reversed-Phase Liquid Chromatography to Achieve Separations Based on One H/D Substitution on Aromatic Hydrocarbons, K. Kimata, T. Hirose, E. Kanao, T. Kubo, K. Otsuka, K. Hosoya, K. Yoshikawa, E. Fukusaki, N. Tanaka*, LCGC Europe, 32(s5), 14-19, 2019

107.

Magnetic-field stimuli-sensitive drug release using a magnetic thermal seed coated with thermal-responsive molecularly imprinted polymer, T. Kubo*, K. Tachibana,T. Naito, S. Mukai, K. Akiyoshi, J. Balachandran, K. Otsuka, ACS Biomater. Sci. Eng., 5, 759-767, 2019

106.

Differentiating π interactions by constructing concave/convex surfaces using a bucky bowl molecule, corannulene in liquid chromatography, E. Kanao, T. Kubo*, T. Naito, T. Matsumoto, T. Sano, M. Yan, K. Otsuka, Anal. Chem., 91, 2439-2446, 2019

105.

Efficient extraction of estrogen receptor-active compounds from environmental surface water via a receptor-mimic adsorbent, a hydrophilic PEG-based molecularly imprinted polymer, M. Yagishita, T. Kubo*, T. Nakano, F. Shiraishi, T. Tanigawa, T. Naito, T. Sano, S. F. Nakayama, D. Nakajima, K. Otsuka, Chemosphere, 217, 204-212, 2019

95.

Specific Intermolecular Interactions by the Localized π-Electrons in C70-fullerene, T. Kubo*, E. Kanao, T. Matsumoto, T. Naito, T. Sano, M. Yan, K. Otsuka, ChemSelect, 1, 5900-5904, 2016

94.

Effect of Acidic Additives on Peak Capacity and Detectivity in Peptide Analysis Using Nano-Flow LC/MS with Low-Density ODS Modified Monolithic Silica Capillary Columns, H. Kobayashi*, M. Sukegawa, K. Fujimura, T. Kubo, K. Otsuka, Chromatography, 37, 133-139, 2016

93.

Validation of Capillary Zone Electrophoretic Method for Evaluating Monoclonal Antibodies and Antibody-Drug Conjugates, K. Kubota,* N. Kobayashi, M. Yabuta, M. Ohara, T. Naito, T. Kubo, K. Otsuka, Chromatography, 37, 117-124, 2016

92.

Effect of Solvents on the Surface Modification of Hydrophilic Macro-Porous Particles with an Ion-Exchange Monomer Having Both Anion and Cation Exchange Groups, K. Shibata, T. Tanigawa, H. Ito, T. Kubo, K. Hosoya*, Chromatography, 37, 99-104, 2016

91.

Three-dimensional fabrication for microfluidics by conventional techniques and equipment used in mass production, T. Naito*, M. Nakamura, N. Kaji, T. Kubo, Y. Baba, K. Otsuka, Micromachines, 7, 82-91, 2016

101.

ELISA-like label-free detection of lysozyme by using a fluorescent monomer-doped molecularly imprinted hydrogel, T. Kubo*, S. Arimura, T. Naito, T. Sano, K. Otsuka, Anal. Sci., 33, 1311-1315, 2017

100.

Tunable separations based on a molecular size effect for biomolecules by poly(ethylene glycol) gel-based capillary electrophoresis, T. Kubo*, N. Nishimura, H. Furuta, K. Kubota, T. Naito, K. Otsuka, J. Chromatogr. A., 1523, 107-113, 2017

99.

Selective Adsorption of Carbohydrates and Glycoproteins via Molecularly Imprinted Hydrogels: Application to a Visible Detection by a Boronic Acid Monomer, T. Kubo*, H. Furuta, T. Naito, T. Sano, K. Otsuka, Chem. Commun., 53, 7290-7293, 2017

98.

Identification and Characterization of a Thermally Cleaved Fragment of Monoclonal Antibody-A Detected by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis, K. Kubota*, N. Kobayashi, M. Yabuta, M. Ohara, T. Naito, T. Kubo, K. Otsuka, J. Pharm. Biomed. Anal., 140, 98-104, 2017

97.

New platform for simple and rapid protein-based affinity reactions, K. Kubota, T. Kubo*, T. Tanigawa, T. Naito, K. Otsuka, Sci. Rep., 7, 178, 2017

96.

Development of a C70-Fullerene Bonded Silica-Monolithic Capillary and its Retention Characteristics in Liquid Chromatography, E. Kanao, T. Naito, T. Kubo*, K. Otsuka, Chromatography, 38, 45-51, 2017T. 

95.

Specific Intermolecular Interactions by the Localized π-Electrons in C70-fullerene, T. Kubo*, E. Kanao, T. Matsumoto, T. Naito, T. Sano, M. Yan, K. Otsuka, ChemSelect, 1, 5900-5904, 2016

94.

Effect of Acidic Additives on Peak Capacity and Detectivity in Peptide Analysis Using Nano-Flow LC/MS with Low-Density ODS Modified Monolithic Silica Capillary Columns, H. Kobayashi*, M. Sukegawa, K. Fujimura, T. Kubo, K. Otsuka, Chromatography, 37, 133-139, 2016

93.

Validation of Capillary Zone Electrophoretic Method for Evaluating Monoclonal Antibodies and Antibody-Drug Conjugates, K. Kubota,* N. Kobayashi, M. Yabuta, M. Ohara, T. Naito, T. Kubo, K. Otsuka, Chromatography, 37, 117-124, 2016

92.

Effect of Solvents on the Surface Modification of Hydrophilic Macro-Porous Particles with an Ion-Exchange Monomer Having Both Anion and Cation Exchange Groups, K. Shibata, T. Tanigawa, H. Ito, T. Kubo, K. Hosoya*, Chromatography, 37, 99-104, 2016

91.

Three-dimensional fabrication for microfluidics by conventional techniques and equipment used in mass production, T. Naito*, M. Nakamura, N. Kaji, T. Kubo, Y. Baba, K. Otsuka, Micromachines, 7, 82-91, 2016

90.

Simple Preparation and Characterization of Viscoelastic Gels Induced by Multiple Intermolecular Interactions Using Low Molecular Weight Species, T. Kubo*, K. Kuroda, T. Naito, S. Mukai, T. Sano, K. Akiyoshi, K. Otsuka, Bull. Chem. Soc. Jpn., 88, 1575-1580, 2015

89.

C60-Fullerene Bonded Silica Monolithic Capillary for Specific Separations of Aromatic Compounds, T. Kubo*, Y. Murakami, T. Naito, K. Otsuka, Chromatography, 36, 105-113, 2015

88.

Selective adsorption of trypsin using molecularly imprinted polymers prepared with PEG-based hydrogels containing anionic functional monomers, T. Kubo*, S. Arimura, T. Naito, K. Otsuka, Mol. Impr., 3, 18-25, 2015

87.

Unique Separation Behavior of a C60-fullerene Bonded Silica Monolith Prepared via an Effective Thermal Coupling Agent, T. Kubo*, Y. Murakami, M. Tsuzuki, H. Kobayashi, T. Naito, T. Sano, M. Yan, K. Otsuka, Chem. Eur. J., 21, 18095-18098, 2015

86.

Molecularly Imprinted Polymer with a Pseudo-template for Thermo-responsive Adsorption/desorption based on Hydrogen Bonding, T. Kubo*, K. Koterasawa, T. Naito, K. Otsuka, Micropor. Mesopor. Mater., 218, 112-117, 2015

85.

Molecularly Imprinted Polymers for Selective Adsorption of Lysozyme and Cytochrome c Using a PEG-Based Hydrogel: Selective Recognition for Different Conformations Due to pH Conditions, T. Kubo*, S. Arimura, Y. Tominaga, T. Naito, K. Hosoya, K. Otsuka, Macromolecules, 48, 4081-4087, 2015

84.

Simple and Effective Label-Free Capillary Electrophoretic Analysis of Sugars by Complexation Using Quinoline Boronic Acids, T. Kubo*, K. Kanemori, R. Kusumoto, T. Kawai, K. Sueyoshi, T. Naito, K. Otsuka, Anal. Chem., 87, 5068-5073, 2015

83.

Hydrodynamic nonadhesive cell retention in a microfluidic circuit for stressless suspension culture, T. Naito*, N. Kaji, M. Tokeshi, T. Kubo, Y. Baba, K. Otsuka, Anal. Methods, 7, 7264-7269, 2015

82.

Variation in Separation Selectivity of Spongy Monoliths Caused by Hydrogen Bonding, K. Hosoya*, A. Taniguchi, T. Tanigawa, T. Kubo, Chromatography, 35, 163-168, 2014

81.

硝酸性窒素吸着能をもつハイブリッド型ポリマーの開発,  岡本みずき,横山理英,久保拓也,細矢憲*,高分子論文集,71, 630-636, 2014

80.

和紙繊維の物質吸着能に関する基礎検討,  大泉百合香,酒井由太郎,久保拓也,細矢憲*,高分子論文集,71, 313-318, 2014

79.

Hydrophilic interaction electrokinetic chromatography using bio-based nanofillers, T. Kawai*, M. Watanabe, K. Uetani, Y. Fukushima, K. Sueyoshi, T. Kubo, F. Kitagawa, H. Yano, K. Otsuka, Electrophoresis, 35, 2229-2236, 2014

78.

Tunable Molecular Sieving in Gel Electrophoresis Using a Poly(ethylene glycol)-Based Hydrogel, T. Kubo*, M. Oketani, Y. Tominaga, T. Naito, K. Otsuka, Chromatography, 35, 81-86, 2014

77.

Quantitative Ligand Immobilization Using Alginate Hydrogel Formed in a Capillary: Application for Online Affinity Concentration, Y. Fukushima*, T. Naito, K. Sueyoshi, T. Kubo, F. Kitagawa, K. Otsuka, Anal. Chem., 86, 5977-5982, 2014

76.

Solvent induced nanostructure formation in polymer thin films: the impact of oxidation and solvent, T. Kubo*, J. Im, X. Wang, J. E. Whitten, K. Otsuka, M. Yan, Colloids Surf. A, 444, 217-225, 2014

75.

Development of a C60-fullerene bonded open-tubular capillary using a photo/thermal active agent for liquid chromatographic separations by π-π interactions, T. Kubo*, Y. Murakami, Y. Tominaga, T. Naito, K. Sueyoshi, M. Yan, K. Otsuka, J. Chromatogr. A, 1323, 174-178, 2014

74.

Effective determination of a pharmaceutical, sulpiride, in river water by online SPE-LC-MS using a molecularly imprinted polymer as a preconcentration medium, T. Kubo*, K. Kuroda, Y. Tominaga, T. Naito, K. Sueyoshi, K. Hosoya, K, Otsuka, J. Pharm. Biomed. Anal., 89, 111-117, 2014,

73.

Rapid Separations on Liquid Chromatography Using Ion-Exchange Media Based on a Spongy Monolith, T. Kubo*, T. Tanigawa, Y. Tominaga, K. Hosoya, K. Otsuka, J. Sep. Sci., 36, 2813-2818, 2013

72.

Synthesis of Poly (ethylene glycol)-Based Hydrogels and its Swelling/Shrinking Properties Responsive for Molecular Recognitions, Y. Tominaga, T. Kubo*, K. Sueyoshi, K. Hosoya, K. Otsuka, J. Polym. Sci. Part A, 51, 3153-3158, 2013

71.

Hybridization of A Macroporous Sponge and Spherical Microporous Adsorbents for High Throughput Separation of Ionic Solutes, T. Kubo*, K. Yasuda, Y. Tominaga, K. Hosoya, K. Otsuka, Anal. Sci., 29, 417-421, 2013

70.

Antibacterial Activities Effectuated by Co-continuous Epoxy-based Polymer Materials, T. Kubo*, K. Yasuda, Y. Tominaga, K. Otsuka, K. Hosoya, Colloids Suf. B, 107, 53-58, 2013

69.

Trace Level Determination of Polycyclic Aromatic Hydrocarbons in River Water with Automated Pretreatment HPLC, Y. Watabe, T. Kubo*, T. Tanigawa, Y. Hayakawa, K. Otsuka, K. Hosoya, J. Sep. Sci., 36, 1128-1134, 2013

68.

Efficient Total Analyses for Bromine Type Flame Retardants by Simple NICI-GC/MS, A. Kobayashi, T. Kubo*, Y. Kitahara, S. Amita, M. Mori, S. Suzuki, K. Otsuka, K. Hosoya, Anal. Methods, 5, 866-873, 2013

67.

Specific chromatographic retentions on polymer pore-surface of macroporous spongy monoliths, T. Tanigawa, T. Kubo, K. Hosoya*, Chem. Lett., 41, 1265-1266, 2012

66.

Synthesis of Novel Polymer Type Sulfoxide Solid Phase Combined with the Porogen Imprinting for Enabling Selective Separation of Polychlorinated Biphenyls, Y. Tominaga, T. Kubo*, A. Kobayashi, K. Yasuda, K. Kato, K. Hosoya, Chemosphere, 89, 378-382, 2012

65.

Fabrication of Glyconanoparticle Microarrays, Q. Tong, X. Wang, H. Wang, T. Kubo, M. Yan*, Anal. Chem., 84, 3049-3052, 2012

64.

Development of Molecularly Imprinted Porous Polymers for Selective Adsorption of Gaseous Compounds, Y. Tominaga, T. Kubo*, K. Yasuda, K. Kato, K. Hosoya, Micro. Meso. Mater., 156, 161-165, 2012

63.

Problems and Improvements of the Regulated Analyses Method on GC for Nonyl Phenol Isomers, A. Kobayashi, Y. Kitahara, K. Toyota, S. Suzuki, T. Kubo*, K. Hosoya, Anal. Methods, 4, 869-872, 2012

62.

Comprehensive research of proteins interacting with Microcystin-LR, T. Mori*, T. Kubo, K. Kaya, K. Hosoya, Anal. Bioanal. Chem., 402, 1137-1147, 2012

61.

Solid phase extraction element based on epoxy polymer monolith for determination of polar organic compounds in aqueous media, T. Takahashi*, K. Odagiri, A. Watanabe, C. Watanabe, T. Kubo, K. Hosoya, J. Sep. Sci., 34, 2925-2932, 2011

60. 

Determination of Bisphenol A with Effective Pretreatment Medium Using Automated Column Switching HPLC with Fluorescence Detection, T. Tanigawa, Y. Watabe, T. Kubo*, K. Hosoya, J. Sep. Sci., 34, 2840-2846, 2011

59.

Polymer-Based Photocoupling Agent for the Efficient Immobilization of Nanomaterials and Small Molecules, T. Kubo, X. Wang, Q. Tong, M. Yan*, Langmuir, 27, 9372-9378, 2011

58.

Fundamental retention properties of macroporous spongy monolith and its application for effective concentration of PAHs, T. Tanigawa, K. Kato, Y. Watabe, T. Kubo*, K. Hosoya, J. Sep. Sci., 34, 2193-2198, 2011

57.

Surface Modification of TiO2 for Selective Photodegradation of Toxic compounds, Y. Tominaga, T. Kubo*, K. Hosoya, Catal. Commun., 12, 785-789, 2011

56.

Polymers of 2-Methacryloyloxyethyl Phosphorylcholine Truly Work as Cell Membrane Mimic ?, T. Mori, T. Kubo, T. J. Konno, K. Hosoya*, Colloids Suf. B, 84, 181-186, 2011

55.

Basic Chromatographic Properties of Polyethylene Glycol-type, Polymer-based Monolithic Columns, T. Mori, T. Kubo, K. Hosoya*, Anal. Sci., 26, 311-316, 2010

54.

Bi-continuous macroporous polymer derived from oligo-ethylene oxide di-vinyl ether by a cationic polymerization, T. Mori, T. Kubo, K. Hosoya*, Colloid Polym. Sci., 288, 1651-1653, 2010

53.

Spontaneous water cleanup using an epoxy-based polymer monolith, T. Kubo*, Y. Tominaga, K. Yasuda, S. Fujii, F. Watanabe, T. Mori, Y. Kakudo, K. Hosoya, Anal. Methods, 2, 570-574, 2010

52.

Co-continuous monolithic titania prepared by organic polymer monolith as pore template, T. Kubo*, N. Tsujioka, N. Tanaka, K. Hosoya, Mater. Lett., 64, 177-180, 2010

51.

Novel Polymer Monolithic Column for Hydrophilic Compounds, T. Kubo*, F. Watanabe, N. Kimura, K. Kaya, K. Hosoya, Chromatographia, 70, 527-532, 2009

50.

Novel separation medium spongy monolith for high throughput analyses, Y. Watanabe, T. Kubo*, K. Kaya, K. Hosoya, J. Chromatogr. A, 1216, 7402-7408, 2009

49.

Basic Properties of A Non-Aromatic Epoxy Polymer-Based Monolithic Capillary Column for µ-HPLC, T. Mori, T. Kubo, M. Sakamoto, K. Kaya, K. Hosoya*, Chromatographia, 70, 699-704, 2009

48.

Effective Recognition on the Surface of a Polymer Prepared by Molecular Imprinting Using Ionic Complex, Y. Tominaga, T. Kubo*, K. Kaya, K. Hosoya, Macromolecules, 42, 2911-2915, 2009

47.

Synthesis of Novel Polymer Type Sulfoxide Solid Phase Combined with the Porogen Imprinting for Enabling Selective Separation of Polychlorinated Biphenyls, T. Ogura, Y. Watabe*, T. Fujita, K. Hosoya, T. Kubo, K. Kaya, BUNSEKIKAGAKU, 58, 293-299, 2009

46.

食用藍藻:髪菜(Nostoc flagelliforme)、イシクラゲ(Nostoc commune)、およびスイゼンジノリ(Aphanothece sacrum)の神経毒 BMAA(β-N-methylamino-L-alanine)の分析,  竹中裕行*,久保拓也医学と生物学,153, 176-179, 2009

45.

Quantitative evaluations of surface-concentrated amino groups on monolithic-type solid supports prepared by copolymerization method, T. Mori, T. Kubo, K. Kaya, K. Hosoya*, Colloid Polym. Sci., 287, 513-523, 2009

44.

Importance of surface properties of affinity resin for capturing a target protein, Cyclooxygenase-1, T. Mori, T. Kubo, K. Kaya, K. Hosoya*, Bioorg. Med. Chem., 17, 1587-1599, 2009

43.

Polymer-based monolithic columns in capillary format tailored by using controlled in situ polymerization, H. Aoki, N. Tanaka, T. Kubo, K. Hosoya*, J. Sep. Sci., 32, 341-358, 2009

42.

Selective Adsorption of Water-soluble Ionic Compounds by Interval Immobilization Technique Based on Molecular Imprinting, T. Kubo*, Y. Tominaga, F. Watanabe, K. Kaya, K. Hosoya, Anal. Sci., 24, 1633-1636, 2008

41.

High Throughput On-line Preconcentration Using ‘‘Spongy-monolith’’ Prepared by Pore Templates, T. Kubo*, F. Watanabe, K. Kaya, K. Hosoya, Chem. Lett., 37, 950-951, 2008

40.

Effective determination method for a cyanobacterial neurotoxin, β-N-methylamino-L-alanine, T. Kubo*, N. Kato, K. Hosoya, K. Kaya, Toxicon, 51, 1264-1268, 2008

39.

Poly(Glycerin 1,3-Dimethacrylate)-Based Monolith with a Bicontinuous Structure Tailored as HPLC Column by Photoinitiated In Situ Radical Polymerization via Viscoelastic Phase Separation, H. Aoki, N. Tanaka, T. Kubo, K. Hosoya*, J. Polym. Sci. Part A, Polym. Chem., 46, 4651-4673, 2008

38. 

Well-Controlled 3D Skeletal Epoxy-Based Monoliths Obtained by Polymerization Induced Phase Separation, N. Tsujioka, N. Ishizuka, N. Tanaka, T. Kubo, K. Hosoya*, J. Polym. Sci. Part A, Polym. Chem., 46, 3272-3281, 2008

37.

Properties of flaky affinity resin with co-continuous structure, T. Mori, A. Tanaka, T. Kubo, K. Kaya, M. Sakamoto, K. Hosoya*, Bioorg. Med. Chem., 16, 1983-1991, 2008

36.

New values of molecular extinction coefficient and specific rotation for cyanobacterial toxin cylindrospermopsin, T. Sano, S. Kikuchi, T. Kubo, H. Takagi, K. Hosoya, K. Kaya*, Toxicon, 51, 717-719, 2008

35.

A Novel Chip Device Based on Wired Capillary Packed with High Performance Polymer-based Monolith for HPLC: Reproducibility in Preparation Processes to Obtain Long Columns, K. Hosoya*, M. Sakamoto, K. Akai, T. Mori, T. Kubo, K. Kaya, K. Okada, N. Tsujioka, N. Tanaka, Anal. Sci., 24, 149-154, 2008

34.

Simple and Effective 3D Recognition of Domoic Acid Using a Molecularly Imprinted polymer, K. Nemoto, T. Kubo*, M. Nomachi, T. Sano, T. Matsumoto, K. Hosoya, T. Hattori, K. Kaya, J. Am. Chem. Soc., 129, 13626-13632, 2007

33.

Novel Polymer Monolith Prepared from a Water-Soluble Crosslinking Agent, T. Kubo*, N. Kimura, K. Hosoya, K. Kaya, J. Polym. Sci. Part A, Polym. Chem., 45, 3811-3817, 2007

32.

Selective Separation of Hydroxy Polychlorinated Biphenyls (HO-PCBs) by the Structural Recognition: Direct separation of the thyroid hormone active analogues from mixtures, T. Kubo*, H. Matsumoto, F. Shiraishi, M. Nomachi, K. Nemoto, K. Hosoya, K. Kaya, Anal. Chim. Acta, 589, 180-185, 2007

31.

Cylindrospermopsin determination using 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethane- sulfonic acid (HEPES) as the internal standard, S. Kikuchi, T. Kubo, K. Kaya*, Anal. Chim. Acta, 583, 124-127, 2007

30. 

Chromatographic separation for domoic acid using a fragment imprinted polymer, T. Kubo*, M. Nomachi, K. Nemoto, T. Sano, K. Hosoya, N. Tanaka, K. Kaya, Anal. Chim. Acta, 577, 1-7, 2006

29.

A Novel Biosurfactant, 2-Acyloxyethylphosphonate, Isolated from Waterblooms of Aphanizomenon flos-aquae, K. Kaya*, L. F. Morrison, G. A. Codd, J. S. Metcalf, T. Sano, H. Takagi, T. Kubo, Molecules, 11, 539-548, 2006

28.

Preparation of glycerol dimethacrylate-based polymer monolith with unusual porous properties achieved via viscoelastic phase separation induced by monodisperse ultra high molecular weight poly(styrene) as a Porogen, H. Aoki, T. Kubo, T. Ikegami, N. Tanaka, K. Hosoya*, D. Tokuda, N. Ishizuka, J. Chromatogr. A, 1119, 66-79, 2006

27.

Fully automated liquid chromatography-mass spectrometry determination of 17beta-estradiol in river water, Y. Watabe, T. Kubo, T. Nishikawa, T. Fujita, K. Kaya, K. Hosoya*, J. Chromatogr. A, 1120, 252-259, 2006

26.

Solvent effects in the preparation of molecularly imprinted polymers for melatonin using N-propionyl-5-methoxytryptamine as the pseudo template, M. Nomachi, T. Kubo, K. Hosoya, K. Kaya*, Anal. Bioanal. Chem., 384, 1291-1296, 2006

25.

Preparation of a novel molecularly imprinted polymer using a water-soluble crosslinking agent, T. Kubo*, K. Hosoya, M. Nomachi, N. Tanaka, K. Kaya, Anal. Bioanal. Chem., 382, 1698-1701, 2005

24.

Selective separation of brominated bisphenol A homologues using a polymer-based medium prepared by the fragment imprinting technique, T. Kubo*, K. Hosoya, T. Sano, M. Nomachi, N. Tanaka, K. Kaya, Anal. Chim. Acta, 549. 45-50, 2005

23.

Selective retention of some polyaromatic hydrocarbons by highly crosslinked polymer networks, K. Hosoya*, H. Aoki, T. Kubo, M. Teramachi, N. Tanaka, J. Haginaka, J. Polym. Sci. Part A, Polym. Chem., 43, 2556-2566, 2005

22.

A new simply and effective fractionation method for cylindrospermopsin analyses, T. Kubo*, T. Sano, K. Hosoya, N. Tanaka, K. Kaya, Toxicon, 46, 104-107, 2005

21.

Novel surface modified molecularly imprinted polymer focused on the removal of interference in environmental water samples for chromatographic determination, Y. Watabe, K. Hosoya*, N. Tanaka, T. Kubo, T. Kondo, M. Morita, J. Chromatgr. A, 1073, 363-370, 2005

20.

Silica monolithic membrane as separation medium Summable property of different membranes for high-performance liquid chromatographic separation, K. Hosoya*, T. Ogarta, Y. Watabe, T. Kubo, T. Ikegami, N. Tanaka, H. Minakuchi, K. Nakanishi, J. Chromatgr. A, 1073, 123-126, 2005

19.

Dependence of the pretreatment efficiency of polymer-based adsorbents for environmental water on their uniformity and size, T. Kubo, K. Hosoya*, Y. Watabe, N. Tanaka, T. Sano, K. Kaya, J. Polym. Sci. Part A, Polym. Chem., 43, 2112-2118, 2005

18. 

Shielded molecularly imprinted polymers prepared with a selective surface modification, Y. Watabe, K. Hosoya*, N. Tanaka, T. Kubo, T. Kondo, M. Morita, J. Polym. Sci. Part A, Polym. Chem., 43, 2048-2060, 2005

17.

LC/MS determination of bisphenol A in river water using a surface-modified molecularly-imprinted polymer as an on-line pretreatment device, Y. Watabe, K. Hosoya*, N.Tanaka, T. Kondo, M. Morita, T. Kubo, Anal. Bioanal. Chem., 381, 1193-1198, 2005

16.

Chromatographic molecular recognition for catechol-related compounds using thiacalix[4]arene as an effective selector, K. Hosoya*, N. Hira, Y. Watabe, N. Tanaka, T. Kubo, K. Kaya, Anal. Bioanal. Chem., 380, 343-345, 2004

15.

A molecular recognition strategy towards Tetra-chlorinated dibenzo-p-dioxins, TCDDs, K. Hosoya*, Y. Watabe, T. Ikegami, N. Tanaka, T. Kubo, T. Sano, K. Kaya, Biosens. Bioelectron, 20, 1185-1189, 2004

14.

An examination of the gelation of methacrylate type crosslinking agents for the preparation of polymer monolith with 3D ordered network structure, H. Aoki, T. Kubo, Y. Watabe, N. Tanaka, T. Norisuye, K. Hosoya*, K. Shimbo, Chem. Lett., 33, 1134-1135, 2004

13.

Interval immobilization technique for recognition toward a highly hydrophilic cyanobacterium toxin, T. Kubo, K. Hosoya*, Y. Watabe, N. Tanaka, H. Takagi, T. Sano, K. Kaya, J. Chromatgr. B, 806, 229-235, 2004

12.

Recognition of hepatotoxic homologues of Microcystin using a combination of selective adsorption media, T. Kubo, K. Hosoya*, Y. Watabe, N. Tanaka, T. Sano, K. Kaya, J. Sep. Sci., 27, 316-324, 2004

11.

Toxicity recognition of hepatotoxins, homologues of Microcystin with artificial trapping devices, T. Kubo, K. Hosoya*, Y. Watabe, N. Tanaka, T. Sano, K. Kaya, J. Environ. Sci. Health, Part A, 39, 2597-2614, 2004

10.

Novel surface-modified molecular imprinted polymer focused on the removal of interferencein environmental water samples, Y. Watabe, K. Hosoya*, N. Tanaka, T. Kubo, T. Kondo, M. Morita, Chem. Lett., 33, 806-807, 2004

9.

Novel surface modification techniques for polymer-based separation media: Stimulus-responsive phenomena based on double polymeric selectors, K. Hosoya*, Y. Watabe, T. Kubo, N. Hoshino, N. Tanaka, T. Sano, K. Kaya, J. Chromatogr. A, 1030, 237-246, 2004

8.

Polymer-based adsorption medium prepared using a fragment imprinting technique for homologues of chlorinated bisphenol A produced in the environment, K. Kubo, K. Hosoya*, Y. Watabe, T. Ikegami, N. Tanaka, T. Sano, K. Kaya, J. Chromatogr. A, 1029, 37-41, 2004

7.

Target selective ion-exchange media for highly hydrophilic compounds: a possible solution through “Interval Immobilization Technique”, T. Kubo, N. Tanaka, K. Hosoya*, Anal. Bioanal. Chem., 378, 84-88, 2004

6.

On-column concentration of bisphenol A with one-step removal of humic acids in water, T. Kubo, K. Hosoya*, Y. Watabe, T. Ikegami, N. Tanaka, T. Sano, K. Kaya, J. Chromatogr. A, 987, 389-394, 2003

5.

A possible purification method of DNAs’ fragments from humic matters in soil extracts using novel stimulus responsive polymer adsorbent, K. Hosoya*, T. Kubo, N. Tanaka, J. Haginaka, J. Pharm. Biomed. Anal., 30, 1919-1922, 2003

4.

Novel surface modification of polymer-based separation media controlling separation selectivity, retentivity and generation of electroosmotic flow, K. Hosoya*, T. Kubo, K. Takahashi, T. Ikegami, N. Tanaka, J. Chromatogr. A, 979, 3-10, 2002

3.

Spiroidesin, a novel lipopeptide from the cyanobacterium Anabaena spiroides that inhibits cell growth of the cyanobacterium Microcystis aeruginosa, K. Kaya*, A. Mahakhant, L. Keovara, T. Sano, T. Kubo, H. Takagi, J. Nat. Prod., 65, 920-921, 2002

2.

Selective surface modification technique for improvement of chromatographic separation selectivity for sugar derivatives, K. Hosoya*, K. Yoshizako, T. Kubo, T. Ikegami, N. Tanaka, J. Haginaka, Anal. Sci., 18, 55-58, 2001

1.

Design for valid “surface” property of polymer-based separation media for capillary electrochromatography (CEC): Correlation between separation selectivity, retentivity and generation of electroosmotic flow, K. Hosoya*, K. Takahashi, T. Kubo, T. Ikegami, N. Tanaka, Chromatography, 22, 187-193, 2001

10.

Hydrogels in electrophoresis: Applications and advances, C. Liu, T. Kubo, K. Otsuka, Anal. Sci., 37, 807-816, 2021

9.

Recent Developments of Point-of-Care (POC) Testing Platform for Biomolecules, Y. Manmana, T. Kubo*, K. Otsuka, Trends Anal. Chem., 135, 116160, 2021

8.

Carbon-based nanomaterials for separation media, E. Kanao, T. Kubo*, K. Otsuka, Bull. Chem. Soc. Jpn., 93, 482-489, 2020

7.

Molecularly Imprinted Materials in Analytical Chemistry, T. Kubo*, Anal. Sci., 33, 1321-1322, 2017

6.

Recent progress for the selective pharmaceutical analyses using molecularly imprinted adsorbents and their related techniques: A review, T. Kubo*, K. Otsuka, J. Pharm. Biomed. Anal., 130, 68-80, 2016

5.

Recent progress in molecularly imprinted media by new preparation concepts and methodological approaches for selective separations of targeting compounds, T. Kubo*, K. Otsuka, Trends Anal. Chem., 81, 102-109, 2016

4.

Molecularly Imprinted Adsorbents for Selective Separation and/or Concentration of Environmental Pollutants, T. Kubo*, K. Hosoya, K. Otsuka, Anal. Sci., 30, 97-104, 2014

3.

Development of Application Techniques Based on Molecular Imprinting for Molecular Selective Pretreatments, T. Kubo*, BUNSEKIKAGAKU, 61, 371-381, 2012

2.

Development and Applications of Fragment Imprinting Technique, T. Kubo*, Chromatography, 29, 9-17, 2008

1.

Development of novel separation media having selective molecular recognition ability, T. Kubo*, BUNSEKI KAGAKU, 53, 1359-1360, 2004

15.

久保拓也,(分担執筆): 国立天文台編『環境年表 2023-2024』10.5 丸善出版,2023

14.

久保拓也,(分担執筆):分析化学実技シリーズ「液体クロマトグラフィー」Chapter 3,共立出版,2022年11月

13.

久保拓也,(分担執筆): 国立天文台編『環境年表 2021-2022』10.5 丸善出版,2021

12.

K. Kimata, E. Kanao, T. Kubo, K. Kozuki, T. Ikegami, M. Furuno, K. Otsuka, N. Tanaka, Isotopic Separations Indicating the Efficiency and Selectivity of HPLC Columns and Stationary Phases, Advances in Chromatography, Volume 57, 2020

11.

久保拓也,(分担執筆): 国立天文台編『理科年表 2020』環境部 114-117,丸善出版,2019

10.

T. Kubo, K. Otsuka, Molecularly Imprinted Materials. In Handbook of Smart Materials in Analytical Chemistry, Vol. 1; de la Guardia, M.; Esteve-Turrillas, F. A., Eds.; Wiley-Blackwell, 2019; Chapter 5.

9.

久保拓也,(分担執筆): 国立天文台編『環境年表 2019-2020』10.3, 10.5, 10.6; 丸善出版,2019

8.

久保拓也, 細矢 憲: 有機化学(化学の基本シリーズ 2); 化学同人: 京都, 2017.

7.

久保拓也,(分担執筆): 国立天文台編『環境年表 平成29-30年』10.3, 10.5, 10.6; 丸善出版,2017

6.

久保拓也,第9章第5節,「HPLC, GCの測定条件設定テクニックと解析 事例集」,技術情報協会,2016年8月

5.

久保拓也,細矢 憲, 大塚浩二,分子インプリントポリマーを用いた残留医薬品の分離・分析 ~選択的な濃縮操作、オンライン分析への応用~, 『製品中に含まれる(超)微量成分・不純物の同定・定量ノウハウ ~試料前処理からデータ解釈まで~』4-9, 技術情報協会, 2014年

4,.

久保拓也,トコトンやさしい イオン交換の本「鋳型樹脂」,B&Tブックス 日刊工業新聞社; pp. 106-107. 2013年

3.

分析化学便覧第6版,4章,8章「薄層クロマトグラフィー」

久保拓也,細矢憲,日本分析化学会,2011年9月

2.

図解 最先端イオン交換技術のすべて“第3章 3-9 鋳型樹脂”

久保拓也,細矢憲,工業調査会,2009年3月

1.

ベーシック 機器分析化学,第0章 18-27

渡部悦幸,細矢憲,久保拓也,化学同人,2008年5月

15.

高分子分子鋳型を用いた環境スクリーニング,高分子“特集 人と地球をつなぐ高分子”2023,72巻,10月号,514-515

14.

スポンジ基材を利用した生体関連ナノ粒子のクロマトグラフィー分離, 化学工業日報(企画記事)2022, September 14, 6-7.

13.

微弱π相互作用を利用した新たな液体クロマトグラフィー分離, 化学工業日報(企画記事)2021, September 15, 6-7.

12.

フラーレンが糖鎖を見分ける ~微弱π相互作用による糖タンパク質分離の可能性化学 76(2), 22-25, 2021

11.

π相互作用の液相分離への応用,日本化学会 分析化学ディビジョン・トピックス,2020年8月

10.

ナノ炭素を用いた分離媒体,ぶんせき“トピックス”2020年6月

9.

エストロゲン受容体結合を模倣した活性選択的分子鋳型の開発と機器分析への活用,Endocrine Disrupter NEWS LETTER,2018年,20巻4号

8.

スポンジモノリスを用いたタンパク質間反応場の新規プラットフォーム,BIO IDUSTRY,2017年9月

7.

分子認識材料の新展開,ぶんせき,2014年9月

6.

スポンジ状分離剤を用いた環境分析の簡便化と高感度化,LC Talk,2013年1月

5.

分子インプリント技術を応用した環境分析技術・浄化材料の開発,月刊ファインケミカルズ【特集】グリーン・サステイナブルケミストリー最前線,2010年12月

4.

環境分析に寄与する新規分離媒体 〜選択的分離と超高速分析~,産業と環境,2008年8月

3.

環境分析・浄化における問題点と対応技術,産業と環境,2007年8月

2.

分析前処理の重要性,問題点と対応技術,産業と環境,2005年8月

1.

微量化学物質の分析の現状と課題,産業と環境,2004年8月

11.

生体微粒子分離精製用多孔性モノリス状ポリマー,生体微粒子分離精製用多孔性モノリス状ポリマーの製造方法,および生体微粒子分離精製用多孔性モノリス状ポリマーを用いるリン脂質で構成された生体微粒子の分離精製法

発明者:久保拓也,谷川哲也,金尾英佑,石濱泰,田中良知

番号:PCT/JP2023/32249

10.

“Separating agent for liquid chromatography, separation column, and method for separating and purifying biopolymer using them”

Hiroshi Kobayashi, Takuya Kubo, Koji Otsuka

US Patent 15891223

9.

「液体クロマトグラフィー用分離剤ならびに分離カラム、及びこれらを用いた生体高分子の分離精製方法」

発明者:久保拓也,小林宏資,大塚浩二

特願2017-021376

8.

「多孔質体、及びこれを用いたモノリス型アフィニティクロマトグラフィ用担体、モノリス型樹脂ビーズ、モノリス型リアクター担体、並びに多孔質体の製造方法」

発明者:久保拓也,谷川哲也,田中良和,大塚浩二

特許出願2016-16736,登録番号6622608

7.

「エポキシ樹脂硬化物多孔体の製造方法」

発明者:久保拓也,細矢憲

特許出願2009-197740,特許公開2011-46856

6.

「エポキシ樹脂硬化物多孔体、水質保持材、抗菌材及びエポキシ樹脂硬化物多孔体の製造方法」

発明者:久保拓也,細矢憲,冨永雄一

特許出願2009-185665(申請済み)

5.

「水溶性架橋剤を用いた高親水性高分子共連続体」

発明者:久保拓也,細矢憲,彼谷邦光

特許出願2007-265340,特許公開2009-91503

4.

「シリンドロスパーモプシンの簡易精製法」

発明者:久保拓也,彼谷邦光

特許出願2005-133881,特許公開2006-308508

3.

「対象化合物を捕捉することができるモレキュラーインプリンテッドポリマー、その調製方法、およびモレキュラーインプリンテッドポリマーにより対象試料中の対象化合物を捕捉する方法」

発明者:久保拓也,細矢憲,彼谷邦光

特許出願2004-326656,特許公開2006-137805

2.

「対象物質を選択的に捕捉する特性を有する高分子材料、分離方法、分離材および選択的固相抽出法」

発明者:久保拓也,細矢憲,狩野文久

特許出願2003-13073,特許公開2004-224875

 

1.

「高分子材料および環境試料の処理方法」

発明者:久保拓也,細矢憲,狩野文久

特許出願2002-18010,特許公開2003-210979

  • JST,CREST(2023~2028年)(代表)
  • 環境省・環境研究総合推進費(2023~2025年)(代表)
  • JST A-Step 産学共同(本格型)(2021~2024年)(研究代表)
  • 科研費 挑戦的研究(開拓)(2020~2022年)(代表)
  • AMED 若手研究者発掘支援事業(2020~2021年)(代表)
  • 京都大学インキュベーションプログラム(2020~2021年)(代表)
  • 環境省・環境研究総合推進費(2019~2021年)(代表)
  • JST,CREST(2017~2023年)(分担)
  • 環境省・環境研究総合推進費(2015~2017年)(分担)
  • 京都大学 融合チーム研究プログラム(2013~2014年)(代表)
  • 科研費 挑戦的萌芽研究(2013~2014年)(代表)
  • 科研費 基盤研究B(2012~2014年)(分担)
  • 環境省 環境研究・技術開発推進費 受託研究(2011~2012年)(分担)
  • 科研費 若手研究A(2007~2008年)(代表)
  • 矢崎科学技術振興記念財団 助成金(2023~2024年)(代表)
  • 豊田理研スカラー共同研究(2021~2022年)(分担)
  • 日立財団,倉田奨励金(2020~2021年)(代表)
  • 豊田理研スカラー(2020~2021年)(代表)
  • the Ajinomoto Innovation Alliance Program(2019年)(代表)
  • 向科学技術振興財団助成金(2019年)(代表)
  • 日本生命財団奨励研究助成(2018~2019年)(代表)
  • 島津財団研究助成(2014年)(代表)
  • クリタ水・環境科学技術財団(2013~2014年)(代表)
  • 旭硝子財団研究助成金(2012年)
  • ホソカワ粉体工学振興財団助成金(2012年)
  • 池谷科学技術振興財団助成金(2007年)

39.

Unique LC separation using specific interaction, T. Kubo, K. Otsuka, HPLC2023, June 20, Düsseldorf, Germany (Keynote Lecture)

38.

Effective separation of glycoproteins due to the difference of sugar chains in liquid chromatography, T. Kubo, K. Otsuka, APCE-CECE-ITP-IUPAC 2022, November 8, Siem Reap (Angkor Wat), Cambodia (Keynote Lecture)

37.

Strategy for using Specific Interactions in Microscale HPLC, T. Kubo, E. Kanao, K. Otsuka, HPLC2022, June 2022, San Diego, CA USA (Keynote Lecture)

36.

Separation of Glycoproteins based on Sugar Chains using Novel Stationary Phases Modified with PEG-conjugated Boronic-acid Derivatives, T. Kubo, K. Otsuka, HPLC2022, June 2022, San Diego, CA USA

35.

Study on specific π-interactions for the efficient separations of aromatic halogens and H/D isotopes, T. Kubo, E. Kanao, T. Naito, M. Yan, K. Otsuka, Pacifichem 2021 (virtual), December 2021 (invited)

34.

Selective separation of an extracellular vesicle, exosome by recognition of surface sugar chains using a spongy monolith, T. Kubo, S. Kato, T. naito, K. Akiyoshi, K. Otsuka, Pacifichem 2021 (virtual), December 2021

33.

Rapid and Effective Separation of Targeting Proteins/Glycoproteins using a Macroporous Sponge Monolith in Liquid Chromatography, T. Kubo, T. Tanigawa, T. Naito, K. Akiyoshi, K. Otsuka, ANALYTICON-2020 Virtual, November 2020, USA (Invited Speaker)

32.

Study on specific p-interactions for the efficient separations of aromatic halogens and H/D isotopes, T. Kubo, E. Kanao, T. Naito, K. Otsuka, HPLC2019KYOTO, December 2019, Kyoto, Japan

31.

Rapid and Effective Separation of Targeting Glycoproteins Using A Macroporous Sponge-Monolith Modified with Lectins in Liquid Chromatography, T. Kubo, S. Kato, T. Tanigawa, T. Naito, K. Otsuka, PREP2019, July 2019, Baltimore, MD USA

30.

CH-π interaction in liquid chromatography for effective shape recognitions and separation of H/D isotopologues, T. Kubo, E. Kanao, T. Naito, M. Yan, N. Tanaka, K. Otsuka, HPLC2019, June 2018, Milan, Italy

29.

Development of New Polymer-based Media for Liquid Phase Separations, T. Kubo, Kyoto University Germany International symposium “KUGIs”, October 2018, Kyoto, Japan

28.

Development of silica-monolithic capillaries modified with poly(ethylene glycol)-conjugated fullerenes for LC separations of glycoproteins, K. Okada, T. Naito, T. Kubo, K. Otsuka, HPLC2018, July 2018, Washington DC, USA

27.

π-Interactions in Liquid Chromatography, T. Kubo, E. Kanao, T. Naito, M. Yan, K. Otsuka, HPLC2018, July 2018, Washington DC, USA

26.

Efective pi-interactions for unique separations in liquid chromatography, T. Kubo, 2018 Sino-Japanese Joint Symposium on Separation Sciences, July 2018, Dalian, China (Keynote Lecture)

25.

Unique Separation Behaviors of Fullerene Bonded Silica Monolith in Liquid Chromatography, T. Kubo, E. Kanao, T. Naito, K. Otsuka, HPLC2017 Jeju, November 2017, Jeju, Korea (invited)

24.

Efficient high throughput separations of IgG using a protein A immobilized spongy monolith in liquid chromatography, T. Kubo, K. Kubota, T. Tanigawa, T. Naito, K. Otsuka, PREP2017, July 2017, Philadelphia, USA

23.

New platform for simple and rapid protein-based affinity reactions, T. Kubo, K. Kubota, N. Nishimura, T. Tanigawa, T. Naito, K. Otsuka, HPLC2017, June 2017, Prague, Czech Republic

22.

Specific retention behaviors of a C70-fullerene bonded silica-monolithic capillary in liquid chromatography, T. Kubo, E. Kanao, H. Kobayashi, T. Naito, M. Yan, K. Otsuka, HPLC2016, June 2016, San Francisco, USA

21.

Characteristic evaluation of PEG-based hydrogels for protein recognition using molecularly imprinting technique, T. Kubo, S. Arimura, T. Naito, K. Otsuka, Pacifichem 2015 meeting, December 2015, Honolulu, Hawaii

20.

Unique separations for aromatic compounds by a C60-fullerene bonded silica-monolithic capillary in liquid chromatography, T. Kubo, M. Tsuzuki, T. Naito, K. Otsuka, Pacifichem 2015 meeting, December 2015, Honolulu, Hawaii

19.

Poly(ethylene glycol)-based Molecularly Imprinted Hydrogels for Selective Adsorption of Proteins, T. Kubo, S. Arimura, T. Naito, K. Otsuka, 43rd Symposium of HPLC and Related Techniques, September 2015, Beijing, China

18.

Specific Liquid Chromatographic Separations by a C60-fullerene Bonded Silica-monolithic Capillary Prepared via Perfluorophenyl Azide, T. Kubo, M. Tsuzuki, T. Naito, M. Yan, K. Otsuka, 2nd Asian Symposium for Analytical Sciences, September 2015, Fukuoka, Japan

17.

Development of CE Methods for High Selective and Sensitive Analyses of Biomolecular Samples, T. Kubo, T. Naito, K. Otsuka, The 8th Asia-Pacific Symposium on Ion Analysis, September 2015, Makuhari, Japan

16.

Specific separations by a C60-fullerene bonded silica-monolithic capillary in liquid chromatography, T. Kubo, Y. Murakami, T. Naito, M. Yan, K. Otsuka, HPLC2015, June 2015, Geneva, Switzerland

15.

Specific Separations by a C60-bonded Silica-monolithic Capillary in Liquid Chromatography, T. Kubo, Y. Murakami, M. Tsuzuki, T. Naito, M. Yan, K. Otsuka, ISMM2015, June 2015, Kyoto, Japan

14.

C60-Fullerene Bonded Silica Monolith for Micro-LC, T. Kubo, Y. Murakami, M. Yan, K. Otsuka, ISPlasma2015, March 2015, Nagoya, Japan

13.

C60-fullerene Bonded Silica-monolith for Liquid Phase Separations, T. Kubo, Y. Murakami, M. Yan, K. Otsuka, APCE2014, December 2014, Kyoto, Japan

12.

Development of aC60-Fullerene Bonded Open-Tubular Capillary Using a Photo/thermal Active Agent for Liquid Chromatographic Separations, T. Kubo, Y. Murakami, K. Otsuka, PITTCON 2014, March 2014, Chicago, IL

11.

Rapid Separations on Liquid Chromatography Using Ion-Exchange Media Based on A Spongy Monolith, T. Kubo, T. Naito, K. Otsuka, 13th Asia Pacific Symposium on Microscale Separation and Analysis, November 2013, Jeju, Korea

10.

Effective liquid chromatographic separation of polycyclic aromatic hydrocarbons by a C60-fullerene coated capillary column, T. Kubo, Y. Murakami, K. Otsuka, CJK 2013 in ASIANALYSIS XII, August 2013, Fukuoka, Japan

9.

Effective liquid chromatographic separation of polycyclic aromatic hydrocarbons by a C60-fullerene coated capillary column, T. Kubo, Y. Murakami, K. Otsuka, CJK 2013 in ASIANALYSIS XII, August 2013, Fukuoka, Japan

8.

Effective separation and photodegradation of water-soluble toxic compounds by the molecularly imprinted adsorbents, T. Kubo, The 6th Shanghai International Symposium on Analytical Chemistry, October 2012, Shanghai, China (Invited speaker)

7.

The basic study of spongy monoliths and its applications, T. Kubo, K. Kato, T. Tanigawa, Y. Watabe, Y. Tanaka, K. Hosoya, ICAS2011, May 2011, Kyoto, Japan

6.

 Selective Adsorption and Degradation of Toxic Compounds by Organic-Inorganic Hybrid Material, T. Kubo, Y. Tominaga, K. Hosoya, The Second French Research Organizations-Tohoku University Joint Workshop on Frontier Materials, December 2009, Sendai, Japan (Invited Speaker)

5.

High Throughput On-line Concentration by Novel Separation Media, Named “Spongy-monolith”, T. Kubo, F. Watanabe, K. Hosoya, HPLC 2008 Kyoto, December 2008, Kyoto, Japan

4.

Effective molecular recognition for ionic compounds by the interval immobilization technique, T. Kubo, Y. Tominaga, K. Hosoya, Molecularly Imprinted Polymers 2008, September 2008, Kobe, Japan

3.

Novel hydrophilic polymer monolith for capillary chromatography, T. Kubo, N. Kimura, K. Kaya, K. Hosoya, 32nd International Symposium on Capillary Chromatography, May 2008, Riva del Garda, Italy (Keynote Lecture)

2.

The effective preparation and quantitative analysis method for cylindrospermopsin as a cyanobacterial toxin, T. Kubo, S. Kikuchi, K. Kaya, XII International IUPAC Symposium on Mycotoxins and Phycotoxins, May 2007, Istanbul, Turkey

1.

Interval Immobilization Technique for Highly Hydrophilic Compounds with Hydrophilic Solvent as Polymerization Porogen, T. Kubo, K. Hosoya, T. Sano, K. Kaya, Molecularly Imprinted Polymers 2004, September 2004, Cardiff, UK (Keynote Lecture)